MITOCHONDRIAL DNA COPY NUMBER OF CUMULUS CELLS IS NOT LINKED TO EMBRYO IMPLANTATION IN GOOD PROGNOSIS IVF PATIENTS

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The mitochondrial DNA content of cumulus granulosa cells is linked to embryo quality.

STUDY QUESTION Could the mitochondrial DNA (mtDNA) content of cumulus granulosa cells (CGCs) be related to oocyte competence? SUMMARY ANSWER The quality of embryos obtained during IVF procedures appears to be linked to mtDNA copy numbers in the CGCs. WHAT IS KNOWN ALREADY Oocyte quality is linked to oocyte mtDNA content in the human and other species, and the mtDNA copy number of the oocyte...

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ژورنال

عنوان ژورنال: Fertility and Sterility

سال: 2020

ISSN: 0015-0282

DOI: 10.1016/j.fertnstert.2020.08.823